Fig. 1 · Structure
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Imatinib-d4
Stable Isotope
Imatinib-d4 is a deuterium-labeled derivative of Imatinib (STI571), designed for use as a stable isotope in research applications. Imatinib serves as a selective inhibitor of tyrosine kinases, primarily targeting BCR/ABL, v-Abl, PDGFR, and c-Kit. This compound is utilized in studying the pharmacokinetics and metabolism of Imatinib, making it valuable for investigations into cancer therapies and kinase signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1134803-16-9 |
| Applications | Stable Isotope |
| Formula | C29H27D4N7O |
| Molecular Weight | 497.63 |
| Synonyms | STI571 d4; CGP-57148B d4 |
| SMILES | O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=C([2H])C([2H])=C(CN5CCN(C)CC5)C([2H])=C4[2H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.