Fig. 1 · Structure
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IMB-XMA0038
MtASADH Inhibitor
IMB-XMA0038 is a selective inhibitor of the mitochondrial aspartate semialdehyde dehydrogenase (MtASADH) with an IC50 value of 0.59 μg/mL. This compound demonstrates potent antibacterial activity against various agent-resistant strains of Mycobacterium tuberculosis, with minimum inhibitory concentrations (MICs) ranging from 0.25 to 0.5 μg/mL. IMB-XMA0038 is ideal for research applications focused on tuberculosis treatment and the development of novel anti-tuberculosis therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 921812-26-2 |
| Applications | MtASADH Inhibitor |
| Formula | C11H10N4O6 |
| Molecular Weight | 294.22 |
| SMILES | [O-][N+](C1=CC=C(C(NC2=NN=C(C3OCCC3)O2)=O)O1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.