Fig. 1 · Structure
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Imidazoleacetic acid hydrochloride
γ-aminobutyric Acid Receptor Agonist
Imidazoleacetic acid hydrochloride is a potent agonist of the γ-aminobutyric acid (GABA) receptor. It functions as a non-competitive inhibitor of GABA transaminase (GABA-T), exhibiting a Ki value of 0.34 mM. This compound effectively increases total free GABA levels in the brain, making it a valuable tool for research into neurological disorders and GABAergic signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 3251-69-2 |
| Applications | γ-aminobutyric Acid Receptor Agonist |
| Formula | C5H7ClN2O2 |
| Molecular Weight | 162.58 |
| Synonyms | Imidazolyl-4-acetic acid hydrochloride |
| SMILES | O=C(O)CC1=CN=CN1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.