Imipramine-d3 hydrochloride is a deuterium-labeled analog of the tricyclic antidepressant imipramine, primarily classified as a stable isotope. This compound exhibits notable biological activity as a Fascin1 inhibitor with potential antitumor effects and acts as a serotonin transporter inhibitor with an IC50 value of 32 nM. Research applications include studies on autophagy induction in U-87MG glioma cells and apoptosis in HL-60 cells, as well as investigations into neuroprotective and immunomodulatory properties.
Imipramine-d3 hydrochloride is a deuterium-labeled analog of the tricyclic antidepressant imipramine, primarily classified as a stable isotope. This compound exhibits notable biological activity as a Fascin1 inhibitor with potential antitumor effects and acts as a serotonin transporter inhibitor with an IC50 value of 32 nM. Research applications include studies on autophagy induction in U-87MG glioma cells and apoptosis in HL-60 cells, as well as investigations into neuroprotective and immunomodulatory properties.
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