Fig. 1 · Structure
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Imipramine-d3 hydrochloride
Stable Isotope
Imipramine-d3 hydrochloride is a deuterium-labeled analog of the tricyclic antidepressant imipramine, primarily classified as a stable isotope. This compound exhibits notable biological activity as a Fascin1 inhibitor with potential antitumor effects and acts as a serotonin transporter inhibitor with an IC50 value of 32 nM. Research applications include studies on autophagy induction in U-87MG glioma cells and apoptosis in HL-60 cells, as well as investigations into neuroprotective and immunomodulatory properties.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 112898-42-7 |
| Applications | Stable Isotope |
| Formula | C19H22D3ClN2 |
| Molecular Weight | 319.89 |
| SMILES | [2H]C([2H])([2H])N(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.