Fig. 1 · Structure
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IMPDH-IN-3
CpIMPDH Inhibitor
IMPDH-IN-3 is a potent inhibitor of C. parvum inosine monophosphate dehydrogenase (CpIMPDH) with an IC50 value of 35 nM. This compound serves as a valuable tool for studying the biochemical pathways associated with Cryptosporidium infections. Its use in research can facilitate the development of novel anti-Cryptosporidium therapies, contributing to the understanding and treatment of cryptosporidiosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 401822-29-5 |
| Applications | CpIMPDH Inhibitor |
| Formula | C18H13ClN4OS |
| Molecular Weight | 368.84 |
| SMILES | O=C(NC1=CC=C(Cl)C=C1)CN2C3=CC=CC=C3N=C2C4=CN=CS4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.