IMR-1

Catalog No.: A16152

Notch inhibitor

IMR-1

IMR-1 Chemical Structure

CAS NO. 310456-65-6

IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 umol/L.

Availability: In stock

Package Price Qty
1 mg
$50.00
2 mg
$70.00
5 mg
$100.00
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Biological Activity

IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 umol/L.
Targets
Notch
26 μM
In vitro DMSO 69 mg/mL (195.24 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.3 mL 141.48 mL 282.96 mL
0.5 mM 5.66 mL 28.3 mL 56.59 mL
1 mM 2.83 mL 14.15 mL 28.3 mL
5 mM 0.57 mL 2.83 mL 5.66 mL

*The above data is based on the productmolecular weight 353.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16152
Actions Inhibitor
CAS No. 310456-65-6
Formula C15H15NO5S2
M. Wt 353.41
Solubility DMSO
Purity >98%
Synonyms IMR1, IMR 1
SMILES O=C(OCC)COC1=CC=C(/C=C(SC(N2)=S)C2=O)C=C1OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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