Fig. 1 · Structure

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IN-2-LF

Lethal factor Inhibitor

IN-2-LF is an inhibitor of lethal factor, an essential component of anthrax toxin. It exhibits an additional inhibitory effect on furin with an IC50 of 2 μM. This compound is valuable for enhancing protection against anthrax lethal toxin, particularly when used in combination with D6R, making it a useful tool for research related to anthrax pathogenesis and toxin inhibition.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 749879-64-9
Applications Lethal factor Inhibitor
Formula C81H150N42O17
Molecular Weight 1984.33
SMILES
[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCNC([C@H](CC1=CC=C(O)C=C1)NC(CNC(C)=O)=O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NO)=O)=O)CC(C)C)=O)[C@@H](C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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