Fig. 1 · Structure
Documents & Downloads
IN04
LRRK1 Inhibitor
IN04 is a selective inhibitor of leucine-rich repeat kinase 1 (LRRK1). By effectively blocking ATP binding to the human LRRK1 kinase domain, IN04 inhibits LRRK1 kinase activity. This compound significantly reduces the bone resorption capabilities of osteoclasts, exhibiting an IC50 value of 5.72 μM. IN04 is suitable for research focused on osteoporosis and related bone metabolism studies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 838816-57-2 |
| Applications | LRRK1 Inhibitor |
| Formula | C20H19N3O6S |
| Molecular Weight | 429.45 |
| SMILES | O=C(OC)C1=CC=CC(NC(CSC2=NN=C(C3=CC(OC)=CC(OC)=C3)O2)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.