Fig. 1 · Structure
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IND81
Antiprion agent
IND81 is an orally active antiprion agent that exhibits an IC50 value of 1.95 μM. This compound effectively reduces abnormal, misfolded forms of prion proteins that contribute to disease pathogenesis. IND81 is pertinent for research applications focused on prion disease and protein misfolding mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1426047-52-0 |
| Applications | Antiprion agent |
| Formula | C18H14N4S2 |
| Molecular Weight | 350.46 |
| SMILES | CC1=CC(NC2=NC(C3=CC=C(C4=CC=CC=N4)S3)=CS2)=NC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.