Fig. 1 · Structure

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Indacrinone

Biochemical Assay Reagent

Indacrinone is a potent diuretic that primarily targets renal transport mechanisms, exhibiting significant saluretic activity. In preclinical studies, it has demonstrated pronounced saluretic effects in rat and dog models, along with both uricosuric and saluretic properties in chimpanzees. This compound is valuable for research applications focusing on kidney function and electrolyte balance. Its unique pharmacological profile offers insights into diuretic mechanisms and potential therapeutic uses in renal disorders.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 56049-88-8
Applications Biochemical Assay Reagent
Formula C18H14Cl2O4
Molecular Weight 365.21
Synonyms MK-196; Indacrynic acid
SMILES
O=C(O)COC1=CC2=C(C(C(C3=CC=CC=C3)(C)C2)=O)C(Cl)=C1Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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