Fig. 1 · Structure
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Indisetron dihydrochloride
5-HT3 receptor antagonist
Indisetron dihydrochloride is a selective antagonist of the 5-HT3 receptor, primarily known for its anti-emetic properties. This compound effectively mitigates nausea and vomiting by blocking the action of serotonin at these receptors. It is widely utilized in research settings to study the mechanisms of nausea and to develop therapies for emesis-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 160472-97-9 |
| Applications | 5-HT3 receptor antagonist |
| Formula | C17H25Cl2N5O |
| Molecular Weight | 386.32 |
| SMILES | CN1C[C@@H]2N(C)[C@H](C1)C[C@@H](C2)NC(C3=NNC4=C3C=CC=C4)=O.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.