Fig. 1 · Structure
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Indoline
Indole Derivative
Indoline is an indole derivative that functions as a key structure for CD4 mimetic compounds (CD4mcs), which facilitate conformational changes in the HIV-1 envelope glycoprotein (Env), leading to viral inactivation. This compound exhibits binding affinity for gp120 and has demonstrated the ability to inhibit HIV-1AD8 with an IC50 in the micromolar range. Indoline is valuable for research applications aimed at understanding and developing treatments for HIV-1 infection.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 496-15-1 |
| Applications | Indole Derivative |
| Formula | C8H9N |
| Molecular Weight | 119.17 |
| SMILES | C12=C(NCC2)C=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.