Indotecan

Catalog No.: A20979

Top1 inhibitor

Indotecan

Indotecan Chemical Structure

CAS NO. 915303-09-2

Indotecan (LMP-400) is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.

Availability: In stock

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5 mg

Regular Price: $405.00

Special Price $324.00

10 mg

Regular Price: $698.00

Special Price $558.40

50 mg

Regular Price: $2,070.00

Special Price $1,656.00

100 mg

Regular Price: $4,140.00

Special Price $3,312.00

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Biological Activity

Indotecan (LMP-400) is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.9 mL 104.5 mL 208.99 mL
0.5 mM 4.18 mL 20.9 mL 41.8 mL
1 mM 2.09 mL 10.45 mL 20.9 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20979
Actions Inhibitor
CAS No. 915303-09-2
Formula C26H26N2O7
M. Wt 478.49
Purity >98%
Synonyms LMP-400, LMP400, LMP 400; NSC-724998, NSC724998, NSC 724998
SMILES O=C1C2=CC(OC)=C(OC)C=C2C3=C(C(C=C(OCO4)C4=C5)=C5C3=O)N1CCCN6CCOCC6
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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