Indotecan

Catalog No.: A20979

Top1 inhibitor

Indotecan

Indotecan Chemical Structure

CAS NO. 915303-09-2

Indotecan (LMP-400) is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.

Availability: In stock

Package Price Qty
5 mg
$405.00
10 mg
$698.00
50 mg
$2,070.00
100 mg
$4,140.00
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Biological Activity

Indotecan (LMP-400) is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.9 mL 104.5 mL 208.99 mL
0.5 mM 4.18 mL 20.9 mL 41.8 mL
1 mM 2.09 mL 10.45 mL 20.9 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20979
Actions Inhibitor
M. Wt 478.49
Formula C26H26N2O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 915303-09-2
Synonyms LMP-400, LMP400, LMP 400; NSC-724998, NSC724998, NSC 724998
SMILES O=C1C2=CC(OC)=C(OC)C=C2C3=C(C(C=C(OCO4)C4=C5)=C5C3=O)N1CCCN6CCOCC6

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