Fig. 1 · Structure
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Infigratinib-Boc
Infigratinib Derivative
Infigratinib-Boc is a derivative of Infigratinib that features a Boc (t-Butyloxycarbonyl) modification. This compound acts as an ATP-competitive pan-FGFR inhibitor, targeting fibroblast growth factor receptors, which are involved in various signaling pathways related to cell proliferation and survival. Infigratinib-Boc is utilized in research applications focused on cancer biology and the development of therapies for FGFR-driven malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2504949-83-9 |
| Applications | Infigratinib Derivative |
| Formula | C29H35Cl2N7O5 |
| Molecular Weight | 632.54 |
| SMILES | O=C(NC1=C(Cl)C(OC)=CC(OC)=C1Cl)N(C)C2=CC(NC(C=C3)=CC=C3N4CCN(C(OC(C)(C)C)=O)CC4)=NC=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.