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Inh2-B1

STK1 Inhibitor

Inh2-B1 is a selective inhibitor of Ser/Thr protein kinase 1 (STK1), targeting its ATP-binding catalytic domain. This compound effectively down-regulates cell wall hydrolase gene expression and significantly disrupts biofilm formation in Methicillin-resistant Staphylococcus aureus (MRSA). Inh2-B1 serves as a valuable tool for elucidating the role of STK1 in bacterial pathogenesis and for investigating therapeutic strategies against resistant bacterial infections.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	690216-38-7
Applications	STK1 Inhibitor
Formula	C₁₉H₁₃N₃O₄S₂
Molecular Weight	411.45
SMILES	O=C(C1=CC(N2C(N3)=C(C(NC4=CC=CC=C4)=O)SC2=S)=C(C=C1)C3=O)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.