Fig. 1 · Structure
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Ionizable lipid-1
Ionizable Lipid
Ionizable lipid-1 is an ionizable lipid with a pKa of 6.16, designed for the formulation of lipid nanoparticles (LNPs) featuring a bilayer structure. This compound facilitates the encapsulation and delivery of nucleotides and other macromolecules, enhancing cellular uptake and stability. It is particularly useful in gene therapy and RNA delivery applications, supporting the development of novel therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2055939-68-7 |
| Applications | Ionizable Lipid |
| Formula | C58H114N2O5 |
| Molecular Weight | 919.54 |
| SMILES | O=C(CCCCCCCCC(CCCCCCCCC(OC(CCCCCC)CCCCCC)=O)N(CCCN(C)C)C(CCCCCCC)=O)OC(CCCCCC)CCCCCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.