IOX 2

IOX 2 Chemical Structure

CAS NO. 931398-72-0

IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $85.00

Special Price $68.00

25 mg

Regular Price: $180.00

Special Price $144.00

50 mg

Regular Price: $320.00

Special Price $256.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH.
Targets
PHD2 (Cell-free assay)
21 nM
In vitro DMSO 7 mg/mL (19.86 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.38 mL 141.92 mL 283.85 mL
0.5 mM 5.68 mL 28.38 mL 56.77 mL
1 mM 2.84 mL 14.19 mL 28.38 mL
5 mM 0.57 mL 2.84 mL 5.68 mL

*The above data is based on the productmolecular weight 352.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A11924
Actions Inhibitor
M. Wt 352.3
Formula C19H16N2O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 931398-72-0
Synonyms IOX-2, IOX2
SMILES C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy IOX 2 | IOX 2 Supplier | purchase IOX 2 | IOX 2 cost | IOX 2 manufacturer | order IOX 2 | IOX 2 distributor | buy 931398-72-0| 931398-72-0 Supplier | purchase 931398-72-0 | 931398-72-0 cost | 931398-72-0 manufacturer | order 931398-72-0 | 931398-72-0 distributor
Rewards