IOX1

Catalog No.: A14277

2OG oxygenases Inhibitor

IOX1

IOX1 Chemical Structure

CAS NO. 5852-78-8

IOX1 is a potent and broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases.

Availability: In stock

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10 mg

Regular Price: $90.00

Special Price $72.00

25 mg

Regular Price: $200.00

Special Price $160.00

50 mg

Regular Price: $355.00

Special Price $284.00

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Biological Activity

IOX1 is a potent and broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases.
Targets
Target Value
KDM3AIC50: 0.1μM
KDM4CIC50: 0.6μM
KDM6BIC50: 1.6μM
KDM2AIC50: 1.8μM
KDM4EIC50: 2.3μM
KDM5CIC50: 19μM
PHD2IC50: 33μM
In vitro DMSO 36 mg/mL (190.3 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 52.86 mL 264.31 mL 528.63 mL
0.5 mM 10.57 mL 52.86 mL 105.73 mL
1 mM 5.29 mL 26.43 mL 52.86 mL
5 mM 1.06 mL 5.29 mL 10.57 mL

*The above data is based on the productmolecular weight 189.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14277
Actions Inhibitor
CAS No. 5852-78-8
Formula C10H7NO3
M. Wt 189.17
Purity >98%
Synonyms IOX 1, Iox-1
SMILES C1=CC2=C(C=CC(=C2N=C1)O)C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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