Fig. 1 · Structure
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IOX2-NH2
IOX2 Derivative
IOX2-NH2 is a derivative of the prolyl hydroxylase-2 (PHD2) inhibitor, IOX2. This compound exhibits specific inhibition of PHD2, playing a crucial role in the regulation of hypoxia-inducible factors (HIFs). IOX2-NH2 is useful for studying cellular responses to hypoxia and investigating the biological pathways involved in cancer and metabolic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 931400-77-0 |
| Applications | IOX2 Derivative |
| Formula | C19H17N3O5 |
| Molecular Weight | 367.36 |
| SMILES | O=C(CNC(C1=C(O)C2=C(C=C(C=C2)N)N(CC3=CC=CC=C3)C1=O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.