Fig. 1 · Structure

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IP-DNQ

NQO1 Inhibitor

IP-DNQ is a selective inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1) that exhibits significant cytotoxicity, particularly against MCF-7 human breast cancer cells, with an IC50 of 0.18 µM. This compound is notably utilized in cancer research to explore mechanisms of tumor cell death and the role of NQO1 inhibition in therapeutic strategies. Its ability to target NQO1 makes it a valuable tool for studies focused on novel anticancer approaches.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1430798-23-4
Applications NQO1 Inhibitor
Formula C19H20N2O4
Molecular Weight 340.37
Synonyms Isopentyl-deoxynboquinone
SMILES
O=C1C=C(C)C(C(C(C(C)=C2)=C3N(CCC(C)C)C2=O)=O)=C(N1)C3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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