Fig. 1 · Structure
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IP7e
Nurr1 Activator
IP7e is a potent Nurr1 activator with a brain-penetrant profile and oral bioavailability, demonstrating an EC50 value of 3.9 nM. This compound enhances Nurr1 transcriptional activity, making it a valuable tool for research in neurodegenerative diseases and neuroinflammation. Its ability to modulate this nuclear receptor positions IP7e as a promising candidate for advancing therapeutic strategies targeting nervous system disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 500164-74-9 |
| Applications | Nurr1 Activator |
| Formula | C23H22N2O4 |
| Molecular Weight | 390.43 |
| SMILES | O=C1C2=C(C=C(C3=CC=C(COCCOC)C=C3)N1C)ON=C2C4=CC=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.