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IPA

Sec18/NSF Inhibitor

Isopropyl alcohol (IPA) acts as a specific inhibitor of Sec18/NSF, effectively binding to phosphatidic acid in a competitive manner. This interaction induces conformational rigidity in Sec18/NSF, impairing its necessary flexibility, which subsequently disrupts SNARE priming and vacuolar membrane fusion. IPA is instrumental for research applications focused on the dynamics of Sec18 activity and the kinetics of SNARE priming.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	200348-48-7
Applications	Sec18/NSF Inhibitor
Formula	C₂₂H₁₈O₇
Molecular Weight	394.38
SMILES	O=C(O)C1C2C=CC(C1C3=C4C=CC(=O)C(O)=C4OC=5C(O)=C(O)C=CC53)C2C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.