Fig. 1 · Structure
Documents & Downloads
IPI-9119
FASN Inhibitor
IPI-9119 is a selective and irreversible inhibitor of Fatty Acid Synthase (FASN), exhibiting an IC50 of 0.3 nM in in vitro assays. This compound demonstrates significant anti-tumor activity in castration-resistant prostate cancer (CRPC) xenograft models, highlighting its potential for therapeutic applications in the treatment of advanced prostate cancer. Researchers may utilize IPI-9119 to investigate the role of FASN inhibition in cancer metabolism and therapeutic resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1346564-56-4 |
| Applications | FASN Inhibitor |
| Formula | C24H19F2N5O5 |
| Molecular Weight | 495.43 |
| SMILES | O=C(O)C1=CC=C(N(C(N2N=NN(C3=C(F)C=CC=C3F)C2=O)=O)C(C)C)C(OC4=CC=CC=C4)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.