Fig. 1 · Structure
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Iproplatin
Anti-cancer Agent
Iproplatin is an anti-cancer agent exhibiting decreased toxicity compared to traditional platinum-based drugs, particularly in the treatment of testicular and ovarian cancers. Its mechanism involves the formation of a reduced product through glutathione conjugation, specifically generating chloro-bis(isopropylamine)glutathionatoplatinum(II). Iproplatin shows potential for investigation in thrombocytopenia and various cancer types, making it a valuable reagent for research in oncology and related fields.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 62928-11-4 |
| Applications | Anti-cancer Agent |
| Formula | C6H20Cl2N2O2Pt |
| Molecular Weight | 418.23 |
| Synonyms | CHIP |
| SMILES | [Cl-][Pt+4]([OH-])([OH-])([NH2]C(C)C)([NH2]C(C)C)[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.