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IQS-019

BCR Kinase Inhibitor

IQS-019 is a potent B cell receptor (BCR) kinase inhibitor. It effectively inhibits the de-phosphorylation of Syk, Lyn, and Btk, both in constitutive and IgM-activated signaling pathways. This compound demonstrates significant biological activity by inhibiting cell proliferation and migration, while also inducing apoptosis. IQS-019 is a valuable tool for cancer research, particularly in the study of B cell lymphomas.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1630804-24-8
Applications	BCR Kinase Inhibitor
Formula	C₂₅H₂₅Cl₂N₇O
Molecular Weight	510.42
SMILES	O=C1C(C2=C(Cl)C=CC=C2Cl)=CC3=C(N)N=C(NC4=CC=C(N5CCN(C)CC5)C=C4)N=C3N1C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.