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Ir-UA

PD-L1 Enhancer

Ir-UA is an iridium(III) complex derived from usnic acid that serves as a PD-L1 enhancer. This compound promotes the expression of PD-L1 by specifically modulating the associated transcription factors, thus facilitating the conversion of "cold tumors" into "hot tumors." Ir-UA is valuable in cancer research, particularly in studies focused on immunotherapy and tumor microenvironment modulation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3033235-42-3
Applications	PD-L1 Enhancer
Formula	C₅₂H₄₃F₆IrN₅O₆P₂+
Molecular Weight	1171.11
SMILES	OC1=C(C(O)=C2C(C)(C(OC2=C1C(C)=O)=CC/3=O)C(C3=C(C)\NCC4=CC=[N](C(C5=[N]6C=CC(C)=C5)=C4)[Ir+3]786(C9=CC=CC=C9C%10=[N]8C=CC=C%10)[N]%11=CC=CC=C%11C%12=CC=CC=C%127)=O)C.[F-][P+5]([F-])([F-])([F-])([F-])[F-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.