Fig. 1 · Structure
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Irbesartan hydrochloride
AT1 Receptor Blocker
Irbesartan hydrochloride is an orally active antagonist of the Angiotensin II type 1 (AT1) receptor. It exhibits antihypertensive properties by promoting vasodilation, thereby reducing blood pressure and enhancing blood and oxygen supply to the heart. This compound is utilized in research focused on hypertension, heart failure, and diabetic nephropathy, making it a valuable tool for investigating cardiovascular and renal pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 329055-23-4 |
| Applications | AT1 Receptor Blocker |
| Formula | C25H29ClN6O |
| Molecular Weight | 464.99 |
| Synonyms | SR-47436 hydrochloride; BMS-186295 hydrochloride |
| SMILES | O=C1N(CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2)C(CCCC)=NC15CCCC5.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.