Fig. 1 · Structure
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IRG1-IN-1
IRG1 Inhibitor
IRG1-IN-1 is a selective inhibitor of immune-responsive gene 1 (IRG1), a key enzyme involved in the metabolism of itaconate. This compound effectively diminishes IRG1 activity, making it a valuable tool for studying metabolic pathways associated with inflammation, cancer, and autoimmune diseases. Its inhibition of IRG1 activity provides insights into the role of this enzyme in immune response regulation and therapeutic potential.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2407652-42-8 |
| Applications | IRG1 Inhibitor |
| Formula | C18H15FO4 |
| Molecular Weight | 314.31 |
| SMILES | O=C(O)/C(C(CC1=CC=CC=C1)C(O)=O)=C\C2=CC=C(F)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.