Fig. 1 · Structure
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Irisolidone
VRAC Blocker
Irisolidone is a major isoflavone derived from Pueraria lobata flowers, acting primarily as a volume-regulated anion channel (VRAC) blocker. Exhibiting potent hepatoprotective activity, Irisolidone demonstrates significant efficacy in inhibiting VRAC with an IC50 value of 9.8 μM. This compound is valuable for research applications focused on cellular volume regulation and related physiological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Blocker |
| CAS Number | 2345-17-7 |
| Applications | VRAC Blocker |
| Formula | C17H14O6 |
| Molecular Weight | 314.29 |
| SMILES | O=C1C(C2=CC=C(OC)C=C2)=COC3=CC(O)=C(OC)C(O)=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.