Fig. 1 · Structure
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(-)-Irofulven
DNA Alkylating Agent
(-)-Irofulven is a DNA alkylating agent that functions as an analog of Illudin S. It effectively inhibits DNA replication and promotes apoptosis in tumor cells, demonstrating significant antitumor activity. This compound is suitable for research applications aimed at understanding cancer biology and developing novel therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 158440-71-2 |
| Applications | DNA Alkylating Agent |
| Formula | C15H18O3 |
| Molecular Weight | 246.31 |
| Synonyms | MGI 114; 6-Hydroxymethylacylfulvene; NSC 683863 |
| SMILES | CC(C1(CC1)[C@@](O)(C2=O)C)=C3C2=CC(C)=C3CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.