Isamoltan hydrochloride is a selective antagonist of the 5-HT1B receptor, exhibiting an IC50 value of 39 nM for the inhibition of [125I]ICYP binding to 5-HT1B recognition sites in rat brain membranes. Additionally, it acts as a β-adrenoceptor ligand with an IC50 of 8.4 nM. This compound demonstrates anxiolytic activity and is valuable in research exploring anxiety-related disorders and serotonergic signaling pathways.
Isamoltan hydrochloride is a selective antagonist of the 5-HT1B receptor, exhibiting an IC50 value of 39 nM for the inhibition of [125I]ICYP binding to 5-HT1B recognition sites in rat brain membranes. Additionally, it acts as a β-adrenoceptor ligand with an IC50 of 8.4 nM. This compound demonstrates anxiolytic activity and is valuable in research exploring anxiety-related disorders and serotonergic signaling pathways.
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