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Ishophloroglucin A

Phlorotannin Compound

Ishophloroglucin A is a phlorotannin compound derived from Ishige okamurae, primarily targeting muscle protein metabolism. This compound has demonstrated the ability to mitigate Dexamethasone-induced muscle atrophy by enhancing protein synthesis via the PI3K/Akt pathway and inhibiting protein degradation through muscle-specific ubiquitin ligases, including muscle RING finger and atrogin-1. Ishophloroglucin A is valuable for research focused on muscle atrophy-related diseases and the mechanisms underlying muscle wasting.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2263882-48-8
Applications	Phlorotannin Compound
Formula	C₉₆H₆₆O₄₈
Molecular Weight	1987.52
SMILES	OC1=CC(O)=C(OC2=CC(O)=C(C(O)=C2)OC3=CC(O)=C(C(O)=C3)OC4=CC(O)=C(C(O)=C4)OC5=CC(O)=C(C(O)=C5)OC6=CC(O)=C(C(O)=C6)OC7=CC(O)=C(C(O)=C7)OC8=C(OC9=C(C=C(C=C9O)OC%10=C(OC%11=C(OC%12=C(OC%13=C(C=C(C=C%13O)OC%14=C(OC%15=C(C=C(C=C%15O)OC%16=CC(O)=CC(O)=C%16)O)C(O)=CC(O)=C%14)O)C=C(O)C=C%12O)C=C(O)C=C%11O)C=C(O)C=C%10O)O)C(O)=CC(O)=C8)C(O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.