Fig. 1 · Structure

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ISIS 329993

C-type Lectin-like Receptors (CTLRs) Inhibitor

ISIS 329993 is an antisense oligonucleotide designed to inhibit C-type lectin-like receptors (CTLRs). This compound has demonstrated significant biological activity in reducing C-reactive protein (CRP) levels, thereby improving clinical outcomes in rodent models of rheumatoid arthritis. It serves as a valuable research tool for investigating the therapeutic potential of CRP modulation in inflammatory diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 827355-42-0
Applications C-type Lectin-like Receptors (CTLRs) Inhibitor
Synonyms ISIS-CRPRx

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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