Fig. 1 · Structure
Documents & Downloads
ISM5939
ENPP1 Inhibitor
ISM5939 is a selective ENPP1 inhibitor, exhibiting an IC50 of 0.63 nM for the degradation of 2,3-cGAMP and 9.28 nM for ATP hydrolysis. This compound demonstrates significant antitumor activity, making it a valuable tool for cancer research and therapy development. Its potency and specificity position ISM5939 as a promising candidate for studies targeting ENPP1-related pathways in tumorigenesis.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2965301-60-2 |
| Applications | ENPP1 Inhibitor |
| Formula | C20H18FN5O3S |
| Molecular Weight | 427.45 |
| SMILES | COC1=C(C2=CC=CC=C2)C3=C(C=N1)N=C(C)N3CC4=C(F)C=C(S(N)(=O)=O)C=N4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.