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Isomaltulose monohydrate

fMLP Inhibitor

Isomaltulose monohydrate is a potent fMLP inhibitor, exerting its effects by disrupting the interaction between the βγ subunit of the fMLP receptor Gi protein and downstream signaling molecules. This compound significantly inhibits fMLP-induced superoxide anion production (IC50: 1.98 μM), cathepsin G release (IC50: 2.76 μM), and chemotaxis, thereby regulating immune responses. Isomaltulose monohydrate also modulates key phosphorylation signals in immune cells, including Src kinase, ERK1/2, p38, and AKT pathways, making it a valuable tool for studying excessive neutrophil activation and inflammation-related processes. Additionally, derivatives of Isomaltulose monohydrate show promise in inhibiting TRPC6 functional mutants associated with FSGS.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	58024-13-8
Applications	fMLP Inhibitor
Formula	C₁₂H₂₄O₁₂
Molecular Weight	360.31
SMILES	OCC([C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)=O.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.