Fig. 1 · Structure

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Isorhynchophylline

Cat. No. A14751 CAS 6859-01-4
Isorhynchophylline, a plant alkaloid with therapeutic potential for cardiovascular and central nervous system diseases.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
HL-60 IC50 > 40 μM Cytotoxicity against human HL60 cells after 48 hrs by MTT assay [PMID: 21070010]
Microglia IC50 19 μM Inhibition of LPS-stimulated NO release in rat cortical microglial cells assessed as nitrite accumulation after 48 hrs [PMID: 18588343]
SW480 IC50 > 40 μM Cytotoxicity against human SW480 cells after 48 hrs by MTT assay [PMID: 21070010]

Specifications

Manufacturer Adooq Bioscience
CAS Number 6859-01-4
Formula C22H28N2O4
Molecular Weight 384.47
SMILES
CC[C@H]1CN2CC[C@@]3([C@@H]2C[C@@H]1/C(=C\OC)/C(=O)OC)C4=CC=CC=C4NC3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

SolventReported Solubility
DMSO 76 mg/mL (197.67 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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