Fig. 1 · Structure
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Isovaleryl-CoA sodium
Succinate:CoA Ligase Inhibitor
Isovaleryl-CoA sodium acts as a succinate:CoA ligase inhibitor, demonstrating an IC50 of 273 μM in rat liver mitochondria. This branched-chain acyl-CoA derivative is utilized in biochemical studies investigating the regulation of metabolic pathways involving succinate and CoA ligase enzymes. Its inhibitory properties make it a valuable tool for research applications in cellular metabolism and energy production.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 6244-91-3 |
| Applications | Succinate:CoA Ligase Inhibitor |
| Formula | C26H44N7O17P3S.xNa |
| Molecular Weight | 851.65 (free base) |
| SMILES | O[C@H]1[C@@H](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CC(C)C)=O)=O)=O)(O)=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.