Fig. 1 · Structure

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ISPA-28

PSAC Antagonist

ISPA-28 is a selective antagonist of the plasmodial surface anion channel (PSAC). This compound binds directly and reversibly to the protein CLAG3, which plays a crucial role in malaria parasite survival. ISPA-28 is utilized in research to study malaria pathogenesis and may aid in the development of new therapeutic strategies against Plasmodium infections.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 1006335-39-2
Applications PSAC Antagonist
Formula C21H24N6O3
Molecular Weight 408.45
SMILES
O=C(C1CC(C2=CN(CC)N=C2C)=NO1)NC3=C(C)N(C)N(C4=CC=CC=C4)C3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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