Fig. 1 · Structure
Documents & Downloads
ISR-IN-1
ISR Inhibitor
ISR-IN-1 is a potent inhibitor of the integrated stress response, exhibiting an EC50 value of 0.6 nM. This compound plays a crucial role in modulating cellular stress pathways, making it a valuable tool for studying stress response mechanisms. ISR-IN-1 is applicable in research exploring the effects of stress on cellular functions and potential therapeutic strategies for stress-related disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1628478-15-8 |
| Applications | ISR Inhibitor |
| Formula | C22H22Cl2F2N2O4 |
| Molecular Weight | 487.32 |
| SMILES | FC(C=C1OCC(N[C@H](CC2)CC[C@@H]2NC(COC3=CC(F)=C(C=C3)Cl)=O)=O)=C(C=C1)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.