ITH12575

Catalog No.: A66041
mNCX Blocker
ITH12575 is a potent and selective blocker of the mitochondrial sodium-calcium exchanger (mNCX). This compound effectively reduces calcium influx through CALHM1 channels at low micromolar concentrations. ITH12575 is valuable for research applications focused on calcium homeostasis, cell signaling, and mitochondrial function.
Grouped product items
Size Price Stock Qty
2mg
$30.00
In stock
5mg
$50.00
In stock
10mg
$80.00
In stock
25mg
$165.00
In stock
50mg
$260.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionITH12575 is a potent and selective blocker of the mitochondrial sodium-calcium exchanger (mNCX). This compound effectively reduces calcium influx through CALHM1 channels at low micromolar concentrations. ITH12575 is valuable for research applications focused on calcium homeostasis, cell signaling, and mitochondrial function.
Product Information
Catalog NumA66041
FormulaC18H18ClNOS
Molecular Weight331.86
CAS Number1802013-08-6
SMILESO=C1NC2=CC=C(Cl)C=C2C(C3=CC=CC=C3C(C)C)SC1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2