Biological Activity
ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors.
Targets
HDAC | ||||
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 34.23 mL | 171.16 mL | 342.33 mL |
0.5 mM | 6.85 mL | 34.23 mL | 68.47 mL |
1 mM | 3.42 mL | 17.12 mL | 34.23 mL |
5 mM | 0.68 mL | 3.42 mL | 6.85 mL |
*The above data is based on the productmolecular weight 292.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16127 |
---|---|
Actions | Inhibitor |
M. Wt | 292.12 |
Formula | C13H7Cl2N3O |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 200626-61-5 |
Synonyms | ITSA1, ITSA 1 |
SMILES | C1=CC=C2C(=C1)N=NN2C(=O)C3=C(C=C(C=C3)Cl)Cl |
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