Fig. 1 · Structure
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Ivabradine metabolite N-Demethyl Ivabradine hydrochloride
Cat. No.
A70230
CAS
1246638-08-3
Drug Metabolite
N-Demethyl Ivabradine hydrochloride is a metabolite of Ivabradine, targeting the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. This compound exhibits significant activity in modulating cardiac rhythm by inhibiting the funny current (If), making it relevant for research in cardiovascular physiology and pharmacology. Its role in understanding drug metabolism and pharmacokinetics enhances its utility in studies related to cardiovascular diseases and treatment responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1246638-08-3 |
| Applications | Drug Metabolite |
| Formula | C26H35ClN2O5 |
| Molecular Weight | 491.02 |
| Synonyms | N-Demethyl ivabradine hydrochloride |
| SMILES | O=C1N(CCCNC[C@@H]2C(C=C(OC)C(OC)=C3)=C3C2)CCC4=CC(OC)=C(OC)C=C4C1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.