IWP-2

Catalog No.: A12707

Wnt inhibitor

IWP-2

IWP-2 Chemical Structure

CAS NO. 686770-61-6

IWP-2 is an inactivator of Porcn function and inhibitor of Wnt production, and blocks beta-catenin accumulation. Wnt/b-catenin ('canonical') pathway maintains transcriptional programs that enable stem cells to remain multipotent.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $50.00

Special Price $40.00

10 mg

Regular Price: $80.00

Special Price $64.00

25 mg

Regular Price: $150.00

Special Price $120.00

100 mg

Regular Price: $450.00

Special Price $360.00

10mM * 1mL in DMSO
$90.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

IWP-2 is an inactivator of Porcn function and inhibitor of Wnt production, and blocks beta-catenin accumulation. Wnt/b-catenin ('canonical') pathway maintains transcriptional programs that enable stem cells to remain multipotent.
Targets
Wnt (Cell-free assay)
27 nM
In vitro DMSO 29 mg/mL (62.15 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.43 mL 107.16 mL 214.32 mL
0.5 mM 4.29 mL 21.43 mL 42.86 mL
1 mM 2.14 mL 10.72 mL 21.43 mL
5 mM 0.43 mL 2.14 mL 4.29 mL

*The above data is based on the productmolecular weight 466.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A12707
Actions Inhibitor
M. Wt 466.6
Formula C22H18N4O2S3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 686770-61-6
Synonyms IWP 2,IWP2
SMILES CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4

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