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IZ-Chol

Ionizable Cationic Lipid

IZ-Chol, an ionizable cationic lipid, is designed to form lipid nanoparticles (LNPs) that effectively complex with DNA. It facilitates endosomal escape through the proton sponge effect, enhancing gene delivery efficiency. IZ-Chol is suitable for use in gene therapy and other applications requiring robust nucleic acid delivery systems.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	191990-35-9
Applications	Ionizable Cationic Lipid
Formula	C₃₄H₅₅N₃O₂
Molecular Weight	537.82
SMILES	C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCCN4C=CN=C4)=O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.