J14

Name: J14
Brand: Adooq Bioscience
SKU: A22706
Rating: 5 (288 reviews)

Catalog No.: A22706

sulfiredoxin inhibitor

J14 is a reversible sulfiredoxin inhibitor with an IC50 of 8.1 μM. J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death.

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Grouped product items
Size	Price	Stock
2mg	$35.00	In stock
5mg	$60.00	In stock
10mg	$90.00	In stock
25mg	$150.00	In stock
50mg	$235.00	In stock
100mg	$405.00	In stock
*10mM 1mL in DMSO**	$70.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	J14 is a reversible sulfiredoxin inhibitor with an IC50 of 8.1 μM. J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death.

Product Information

Catalog Num	A22706
Formula	C28H25ClN4O2S
Molecular Weight	517.04
CAS Number	1043854-13-2
SMILES	O=C(O)C1=CC=C(CSC2=NC(C3=CC=CC=C3)=CC(N4CCN(C5=CC=CC=C5Cl)CC4)=N2)C=C1
Synonyms	J 14,J-14
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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