J14

Catalog No.: A22706
sulfiredoxin inhibitor
J14 is a reversible sulfiredoxin inhibitor with an IC50 of 8.1 μM. J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death.
Grouped product items
Size Price Stock Qty
2mg
$35.00
In stock
5mg
$60.00
In stock
10mg
$90.00
In stock
25mg
$150.00
In stock
50mg
$235.00
In stock
100mg
$405.00
In stock
10mM * 1mL in DMSO
$70.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription J14 is a reversible sulfiredoxin inhibitor with an IC50 of 8.1 μM. J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death.
Product Information
Catalog Num A22706
Formula C28H25ClN4O2S
Molecular Weight 517.04
CAS Number 1043854-13-2
SMILES O=C(O)C1=CC=C(CSC2=NC(C3=CC=CC=C3)=CC(N4CCN(C5=CC=CC=C5Cl)CC4)=N2)C=C1
Synonyms J 14,J-14
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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