Fig. 1 · Structure
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J147 (E-isomer)
Neuroprotective Agent
J147 is a highly potent, orally bioavailable neuroprotective agent primarily targeting cognitive enhancement. It effectively crosses the blood-brain barrier, allowing for significant influence on central nervous system processes. J147 inhibits monoamine oxidase B (MAO B) and the dopamine transporter, displaying therapeutic potential for Alzheimer's disease (AD) and other neurodegenerative conditions. Its neuroprotective properties make it a valuable tool for research in the field of cognitive disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1807913-16-1 |
| Applications | Neuroprotective Agent |
| Formula | C18H17F3N2O2 |
| Molecular Weight | 350.33 |
| SMILES | COC1=CC=CC(/C=N/N(C2=C(C=C(C=C2)C)C)C(C(F)(F)F)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.