Fig. 1 · Structure
Documents & Downloads
JA2
MEP Inhibitor
JA2 is a selective inhibitor of metalloendopeptidase 24.15, which enhances the hypotensive response to bradykinin in rat models. This compound serves as a valuable tool for investigating the role of metalloendopeptidases in vascular biology and cardiovascular research. Its ability to modulate blood pressure responses makes JA2 relevant for studies related to hypertension and related therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 277333-45-6 |
| Applications | MEP Inhibitor |
| Formula | C33H38N4O8 |
| Molecular Weight | 618.68 |
| SMILES | OC(C=C1)=CC=C1C[C@H](NC(C(C)(C)NC([C@H](C)NC(C(O)=O)CCC2=CC=CC=C2)=O)=O)C(NC3=CC=C(C=C3)C(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.