Pyridone 6 (JAK Inhibitor I)

Catalog No.: A13457

JAK inhibitor

Pyridone 6 (JAK Inhibitor I)

Pyridone 6 (JAK Inhibitor I) Chemical Structure

CAS NO. 457081-03-7

JAK Inhibitor I is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK1, JAK2, and JAK3.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $180.00

Special Price $162.00

10 mg

Regular Price: $270.00

Special Price $243.00

25 mg

Regular Price: $540.00

Special Price $486.00

50 mg

Regular Price: $780.00

Special Price $702.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

JAK Inhibitor I is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK1, JAK2, and JAK3.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.33 mL 161.66 mL 323.31 mL
0.5 mM 6.47 mL 32.33 mL 64.66 mL
1 mM 3.23 mL 16.17 mL 32.33 mL
5 mM 0.65 mL 3.23 mL 6.47 mL

*The above data is based on the productmolecular weight 309.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13457
Actions Inhibitor
M. Wt 309.3
Formula C18H16FN3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 457081-03-7
Synonyms Merck-5,Pyridone 6,DBI
SMILES CC(C)(C)C1=NC2=C(N1)C3=C(C=C(C=C3)F)C4=C2C=CNC4=O

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