JAK1-IN-4

Name: JAK1-IN-4
Brand: Adooq Bioscience
SKU: A18821
Rating: 5 (288 reviews)

Catalog No.: A18821

JAK1 inhibitor

JAK1-IN-4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively. JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM).

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Grouped product items
Size	Price	Stock
1mg	$315.00	In stock
5mg	$680.00	In stock
10mg	$1,095.00	In stock
25mg	$1,665.00	In stock
50mg	$2,175.00	In stock
100mg	$2,795.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

Targets

Target	Value

Product Information

Catalog Num	A18821
Formula	C26H32FN9O2
Molecular Weight	521.59
CAS Number	2091134-35-7
SMILES	O=C(NC1=CC=CC2=C1NC=C2C3=C(C=NC(NC4=CN(N=C4OC)C)=N3)F)[C@H](N5CCN([C@@H](C5)C)C)C
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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