JAK3 covalent inhibitor-1

Name: JAK3 covalent inhibitor-1
Brand: Adooq Bioscience
SKU: A18926
Rating: 5 (288 reviews)

Catalog No.: A18926

JAK3 covalent inhibitor

JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.

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JAK3 covalent inhibitor-1 2300106-50-5 JAK3 covalent inhibitor

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Grouped product items
Size	Price	Stock
1mg	$315.00	In stock
5mg	$955.00	In stock
10mg	$1,595.00	In stock
25mg	$2,715.00	In stock
50mg	$3,575.00	In stock
100mg	$4,895.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description

JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.

Targets

Target	Value

Product Information

Catalog Num	A18926
Formula	C22H17FN6O2S
Molecular Weight	448.47
CAS Number	2300106-50-5
SMILES	O=S(N[C@H](C[C@@H]1NC#N)C(C1=C2)=CC=C2C3=C4C(NC=C4)=NC=N3)(C5=CC=CC(F)=C5)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂