JAK3 covalent inhibitor-1

Catalog No.: A18926

JAK3 covalent inhibitor

JAK3 covalent inhibitor-1

JAK3 covalent inhibitor-1 Chemical Structure

CAS NO. 2300106-50-5

JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.49 mL 222.98 mL
0.5 mM 4.46 mL 22.3 mL 44.6 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18926
Actions Inhibitor
M. Wt 448.47
Formula C22H17FN6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2300106-50-5
Synonyms 0
SMILES O=S(N[[email protected]](C[[email protected]@H]1NC#N)C(C1=C2)=CC=C2C3=C4C(NC=C4)=NC=N3)(C5=CC=CC(F)=C5)=O

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